Prognosis Kanker Ovarium Stadium Lanjut dalam Perspektif Biomarker Molekular: Kajian Ekspresi CD117, CD133, CD24, CD44, dan ALDH

Authors

dr. Kade Yudi Saspriyana, M. Biomed, SpOG Subsp Onkologi
RS Ngoerah Bali
Dr. dr. I Nyoman Gede Budiana, Sp.OG (K) Onk
Gynecology Oncology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Udayana University, Ngoerah Hospital, Bali
Prof. Dr. dr. Novi Silvia Hardiany, M.Biomed
Department of Biochemistry and Molecular Biology Faculty of Medicine Universitas Indonesia
Dr. dr. Aria Kekalih, M.T.I. SpKKLP
Department of Community Medicine Faculty of Medicine Universitas Indonesia
dr. Tricia Dewi Anggraeni, Sp.OG (K) Onk
Gynecology Oncology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital Jakarta
DR.dr. Lisnawati, Sp.P.A., Subsp. Kv.R.M. (K)
Department of Pathological Anatomy Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital Jakarta
Prof. Dr. dr Hariyono Winarto, Sp.OG, Subsp.Onk (K)
Gynecology Oncology Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital Jakarta

Keywords:

Kanker Ovarium Tipe Epitel, Sel Punca Kanker, CD117, CD133, CD24, CD44, ALDH, Progression Free Survival

Synopsis

Prognosis Kanker Ovarium dalam Perspektif Biomarker Molekuler: Kajian Ekspresi CD117, CD133, CD24, CD44, dan ALDH merupakan monografi ilmiah yang membahas peran biomarker molekuler dalam memahami patogenesis dan prognosis kanker ovarium epitel stadium lanjut. Buku ini menyoroti pentingnya konsep cancer stem cell (CSC) atau sel punca kanker yang diyakini berperan dalam pertumbuhan tumor, resistensi terapi, kekambuhan penyakit, serta luaran klinis pasien.

Melalui pendekatan ilmiah yang sistematis, buku ini mengulas berbagai aspek penting, mulai dari epidemiologi kanker ovarium, konsep dasar sel punca kanker, hingga kajian ekspresi biomarker CSC seperti CD117, CD133, CD24, CD44, dan ALDH. Pembahasan juga mencakup metode penelitian berbasis imunohistokimia serta analisis statistik yang digunakan untuk menilai hubungan antara ekspresi biomarker dengan prognosis dan kemungkinan kekambuhan penyakit.

Dengan memadukan kajian teoretis dan analisis penelitian, buku ini memberikan gambaran yang komprehensif mengenai potensi biomarker molekuler dalam mendukung penentuan prognosis dan pengembangan terapi target di masa depan. Buku ini ditujukan bagi dokter spesialis, residen, mahasiswa kedokteran, peneliti biomedis, serta tenaga kesehatan yang memiliki minat dalam bidang onkologi ginekologi.

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  • MED058160 Medical / Nursing / Oncology & Cancer

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April 16, 2026

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